Similac Sensitive Vs Total Comfort- Which One Should You Go For?

Similac Sensitive Vs Total Comfort

No one is ready to compromise when it comes to their babies. However, when the baby is sensitive regarding foods, it becomes a more delicate subject. Fortunately, Similac offers formulas that suit sensitive babies very well.  My name is Sharon Dunn and I want to talk today about Similac baby formula options for you and your family.

Both Similac Total Comfort and Similac Sensitive are unique formulas for babies with a sensitive tummy. However, there are some primary differences between them. 

This article creates a clear differentiation between Similac Sensitive vs Total Comfort to help you decide which one is more appropriate for your baby. 

Table of Contents

Similac Sensitive Vs Total Comfort

If you are struggling with your baby’s gassy tummy, Similac is something that would definitely be on your bucket list. Among several other reasons, Similac is immensely popular among parents and often suggested by pediatricians. 

The question is, which one between Similac Sensitive and Similac Total Comfort is the better one in comparison? First, let’s have an overview of each of the formulas. 

Similac Pro Sensitive

Similac Pro Sensitive contains nucleotides and prebiotics, much like those found in breast milk. The prebiotics present in Similac Sensitive helps your baby with his/her digestion. 

The nucleotides, on the other hand, are for a healthy immune system. So, both these ingredients together help your baby’s overall health. 

The first ingredient of Similac Sensitive is dehydrated corn syrup. It’s different from regular corn syrup, which is high in fructose. It works as a sweetener in the formula as an alternative to lactose. This corn syrup also makes Similac Sensitive more sugary than Total Comfort. 

The milk protein in Similac Sensitive is free from lactose and certain minerals that make it more tolerable for lactose-intolerant babies. 

The Good Sides

  • Reasonable price: Similac Sensitive will indeed come first if it’s affordability we’re considering. It comes in different sizes, powder and liquid form, and the price is within reach.  
  • Non-GMO ingredients: Unlike many other milk formulas, Similac Sensitive is free from any GMO ingredients, making it entirely safe for your baby.  
  • Rich in vital nutrients: It’s filled with all the essential nutrients necessary for your baby’s natural growth.  
  • Similar to breast milk: All the components in Similac Sensitive make it a suitable substitute for breast milk. 
  • Perfect for gassy baby stomach: Newborns who have gas problems and acts fussy can benefit from Similac Sensitive because the formula requires less work to digest.  

The Not So Good Sides

  • Some infants may not digest it well: It contains both whey and casein, so some babies may find it difficult to digest it. 
  • Not suitable for babies with Galactosemia: This formula is strictly prohibited for any babies with Galactosemia. 

Similac Pro Total Comfort

Infants who struggle with digesting milk can conveniently consume the Similac Pro Total Comfort. It contains partially hydrolyzed protein to make it easy on the baby’s stomach. Babies with Celiac disease can also benefit from this formula because it doesn’t have any gluten. 

Total Comfort contains corn maltodextrin as its first ingredient and whey protein hydrolysate as its second. Corn Maltodextrin comes from corn that contains sugar less than 20%. 

Besides, it helps the formula to become more like milk in texture. The ingredients help your baby by providing energy without any syrup that contains sugar. 

Another vital ingredient to mention is hydrolysate protein. The amino acid bonds of the protein break down when heated and make the formula easy to digest by the baby. 


  • Suitable breast milk substitution: The components in this formula are similar to breast milk ingredients, making it an ideal substitution for breast milk. 
  • Vital Components: It contains all of the vital nutrients for your baby’s healthy growth. It builds a healthy immune system for the baby and helps them digest the milk without any discomfort. 
  • Free from artificial hormones: Similac Total Comfort does not have any synthetic hormones to accelerate the baby’s natural growth. 
  • Free from gluten: Babies with gluten intolerance can consume and digest this milk without facing any discomfort. 
  • Available in liquid form, too: If you ever want to avoid the hassle of preparing the milk, it comes in a liquid form too. The liquid form is ready to feed. 
  • It helps develop the brain and the eyes: The formula is rich in essential nutrients to make it more helpful in your baby’s growth. 


  • Not suitable babies with Galactosemia: Much like the Similac Sensitive, this one isn’t suitable for babies with Galactosemia too. 
  • Comparatively expensive: Because of its advanced formula and ingredients, it’s somewhat costly than Similac Sensitive.  

Similac Sensitive Vs Total Comfort Verdict

When comparing the two, you need to consider all vital components and features of the formulas. Let’s look at the comparison chart before moving forward. 

Similac Total Comfort

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Similac Sensitive

Check Price

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Similac Total ComfortCheck Price
NatureSome babies may face difficulties digesting itGentle on stomach
Sugar contentHighLow
Corn syrupA high amount of corn syrupNo corn syrup
Available inPowder and liquid, different sizes Powder and liquid
Perfect forBabies with gassy and fussy stomachBabies with digestion issues
ConsistencyThicker than Total ComfortNot as thick when mixed with water

Let’s have a closer look at the differences between these two formulas. 


Both formulas have certain smells. However, the scent you get from Total Comfort is not too sharp, so babies may not even notice it. 

On the contrary, the smell Similac Sensitive comes with is a tin-like smell. It’s primarily because of the container it comes in. However, if your baby is sensitive about smells, he/she may not like the formula. 


Both formulas are for babies with sensitives stomachs. The ingredients make the digestion process more accessible because the milk proteins are already broken down. 

There are two ingredients in milk protein, namely casein, and whey. Total Comfort only uses isolated whey, making it easier for your baby to digest it. In comparison, Similac Sensitive contains both casein and whey, which can be a bit difficult for some babies to digest.


If we’re talking about vital nutrient components, both of the formulas have them. The components help the baby grow and build an immune system like babies who feed breast milk. 

However, Total Comfort has the upper hand here when it comes to sugar content. It does not contain any corn syrup, and the sugar content is low in amount. 

In comparison, Similac Sensitive is high in sugar content because it comes with a high amount of corn syrup. 

So, if your baby prefers sweet, you can try Similac Sensitive. On the other hand, if you don’t want to include corn syrup in your baby’s food, choose Total Comfort. 


This may be the only feature where there’s no difference between the two. Both formulas come in powder form and ready to eat liquid form. 

If you do not want to go through the hassle of mixing and preparing the milk, you can go for the liquid form of any of the two.

Note that you will find Similac Sensitive in different sizes, whereas Total Comfort only comes in one size.  


The price is always an issue. As you can guess, Similac Total Comfort is comparatively expensive than Similac Sensitive. So, if the price is something you’re worried about, Similac Sensitive offers you a more affordable deal than Total Comfort. 

Similac Sensitive Vs Total Comfort: Which One To Go For?

If you’re looking for a winner here, Total Comfort is better in almost every aspect. However, there’s one minor issue with it, the price. 

If price is not something you would care about, Total Comfort is a viable choice for you. In comparison, if your baby can digest Similac Sensitive without any discomfort, you can get that one too.

Babies with more sensitive tummies will benefit from Total Comfort the most. Even though it’s a bit expensive, it’s comparatively a better choice in every aspect. 

Similac Sensitive is viable for gassy and fussy babies. If they can digest it, it’s an affordable option, and there’s no reason for you not to choose it. 

However, if you don’t want high sugar content in your baby’s food, I must recommend Total Comfort. 

So, which one you should go for depends on your budget and your baby’s preference. Also, taking suggestions from an authorized pediatrician can also give you a good perspective!

Final Verdict

In comparing Similac Sensitive vs Total Comfort, the latter will always win if we ignore the price. But, unfortunately, price isn’t a minor aspect that we can ignore. 

You should remember that Total Comfort being the better option doesn’t mean Similac Sensitive isn’t something you should consider. If your baby can digest it without any issues, why shouldn’t you go for a more affordable option? 

Take your time to compare the pros and cons before you get your baby the best milk formula. Also, we highly recommend to consult with a pediatrician before finalizing your choice of milk formula.

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